Least-Squares fitting of biophysical parameters in a neuron

Robert G. Smith

To obtain the best correspondence between a model of a neuron and the data recorded from the neuron, the model must include a realistic morphology along with estimates of the neuron's biophysical parameters. To accomplish the best estimates of the internal axial resistivity Ri, membrane resistivity Rm, and the membrane capacitance, as well as several other parameters,....



Rob Smith

rob<at>retina.anatomy.upenn.edu